Clinical outcomes following regenerative therapy of non-contained intrabony defects using a deproteinized bovine bone mineral combined with either enamel matrix derivative or collagen membrane. A randomized controlled clinical trial.
Not Applicable
- Conditions
- intrabony defectsK05.3Chronic periodontitis
- Registration Number
- DRKS00005214
- Lead Sponsor
- niversity of Naples Federico II
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Chronic periodontitis
FMPS = 20 % at baseline
FMBS = 20 % at baseline
Non-contained osseous defect with an intrabony component = 3 mm located in the interproximal area of single-rooted teeth including first maxillary premolars and flat surfaces of molar teeth
Presence of = 2 mm of keratinized tissue
Exclusion Criteria
Relevant medical conditions contraindicating surgical interventions
Pregnancy or lactation
Tobacco smoking
Interproximal intrabony defects extending into the furcation area of molar teeth
Untreated periodontal conditions
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gain in clinical attachment level measured with a graduated probe in mm at tooth sites with non-contained intrabony defects at baseline and after 12 months.
- Secondary Outcome Measures
Name Time Method Residual probing pocket depth (PPD) in mm at tooth sites with non-contained intrabony defects after 12 months.