Influencing Factors of the Diagnostic Accuracy of Novel Coronary Functional Evaluation Methods: a Cross-sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 500
- 主要终点
- the discordance between fractional flow reserve and quantitative flow ratio
研究概览
简要总结
In this study, patients were retrospectively included, univariate and multivariate analysis of factors affecting their diagnosis inconsistencies was performed, and a new diagnostic model was constructed by logistic regression.
详细描述
The evaluation of coronary function is becoming more and more important in the guidelines, in which coronary flow reserve (FFR) is the gold standard for diagnosis, but its measurement process requires the application of adenosine, vasodilator, etc. Some patients cannot be measured because of asthma and low blood pressure. A new instantaneous wave-free ratio (iFR), contrastive flow reserve fraction (cFFR) and quantitative flow fraction (QFR) have been developed for the evaluation of coronary function. However, in some patients, the new coronary function evaluation methods were inconsistent with FFR. In this study, patients were retrospectively included, univariate and multivariate analysis of factors affecting their diagnosis inconsistencies was performed, and a new diagnostic model was constructed by logistic regression.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age above 18 and below 80 years old, regardless of gender;
- •FFR was detected by coronary angiography;
- •The coronary angiography images were clear, meeting the requirements of QFR analysis or detecting iFR, cFFR, and resting pd/pa during the operation.
排除标准
- •Coronary artery bypass graft (CABG);
- •Atrial fibrillation or flutter;
- •Left or right coronary opening lesions;
- •Pregnancy or breastfeeding.
结局指标
主要结局
the discordance between fractional flow reserve and quantitative flow ratio
时间窗: When the patient has completed coronary angiography and received a diagnosis
If FFR≤0.80 and QFR ≤0.8 or FFR \> 0.80 and QFR \> 0.8 are consistent groups, otherwise they are inconsistent group
次要结局
未报告次要终点