NCT00721643已完成早期 1 期
Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)
适应症
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Plasma quercetin
研究概览
简要总结
The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy subjects (>60 yr, n=5)
- •subjects with metabolic syndrome (>60 yr, n=5)
- •Subjects who has
- •high fasting plasma glucose (>5.6 mmol/L),
- •central obesity (waist-hip ratio, >0.9 for men, >0.85 for women)
- •either high blood pressure (>130/85 mmHg) or high triacylglycerol (>1.7 mmol/L) will be selected to have metabolic syndrome.
- •normal hematological parameters, normal serum albumin, normal liver function, and normal kidney function
- •no history of smoking or alcoholism.
排除标准
- •consume >7 alcoholic drinks/wk
- •taking cholesterol medication or hormone replacement
结局指标
主要结局
Plasma quercetin
时间窗: 0, 30, 60, 100, 180, 240, 300, 360, 420 & 480 min
次要结局
未报告次要终点
研究者
研究点 (2)
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