Effects of pilates training and turmeric supplementation on SIRT1, Klotho gene and Quality of life
Not Applicable
Not yet recruiting
- Conditions
- Aging.
- Registration Number
- IRCT20180218038785N1
- Lead Sponsor
- Deputy of Research and Technology Development of Tabriz University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 48
Inclusion Criteria
Age range of 35 to 55 years
Being Overweight( BMI: 25-30 kg/m²)
Without regular physical activity
No drug and supplementation
Having menstrual period
Exclusion Criteria
illness
allergy to spices
Unwillingness or person's cooperation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sirtuin1. Timepoint: Before and after the intervention (3 month later). Method of measurement: Sirtuin 1 content will be measured by using Human Sirtuin1 ELISA kit, made by Shanghay Crystal D company.;Serum Klotho gene. Timepoint: Before and after the intervention (3 month later). Method of measurement: Human Klotho ELISA kit, made by Shanghay Crystal D company.;Quality of life. Timepoint: Before and after the intervention (3 month later). Method of measurement: Quality of life questionare.
- Secondary Outcome Measures
Name Time Method Weight. Timepoint: Before and after intervention (3 month later). Method of measurement: With Omron Digital Scale.;Body fat percent. Timepoint: Before and after intervention (3 month later). Method of measurement: Using body composition analyzer.;Fat-free mass. Timepoint: Before and after intervention (3 month later). Method of measurement: Using body composition analyzer.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does pilates training modulate SIRT1 and Klotho gene expression in aging populations?
What comparative effectiveness data exist for turmeric supplementation versus standard lifestyle interventions in middle-aged overweight females?
Which biomarkers correlate with SIRT1/Klotho pathway activation in response to combined pilates and curcumin therapy?
What adverse events are associated with 12-week pilates regimens and turmeric supplementation in clinical trials?
How do SIRT1 activators like curcumin synergize with exercise interventions for aging-related quality of life improvement?