The Effectiveness of Tibial Nerve Mobilization in Patients With Tarsal Tunnel Syndrome

Not Applicable

Completed

• Conditions: Nerve Compression Syndromes; Neuropathic Pain
• Interventions: Other: Tibial Nerve Mobilization; Other: Foot-ankle range of motion exercises

• Registration Number: NCT05307354
• Lead Sponsor: Kutahya Health Sciences University

Brief Summary

This randomized, clinical, single-blinded, controlledstudywasinitiallyplannedtoinclude 35 patients diagnosed with tarsal tunnel who applied to Kütahya Health Sciences University, Evliya Çelebi Training and Research Hospital, Physical Medicine and Rehabilitation outpatient clinic.Patients aged 20-55 years who were diagnosed with tarsal tunnel syndrome by electromyography (EMG) in the last 6 months were included in the study. The patients were randomized into two groups using the computer-assisted randomization method. Tibial nerve mobilization and foot-ankle range of motion exercises will be given to the study group, and only foot-ankle joint range of motion exercises will be given to the control group. All the patients were evaluated with the Visual Analog Scale (VAS), Foot Functional Index (FFI), Neuropathic Pain QuestionnaireN (NPQ) and Tibial Nerve ultrasonography before the intervention and at the fourth week of intervention.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-03
• Study First Submitted: 2022-03-24
• Study First Submitted QC: 2022-03-24
• Study Start: 2022-04-01
• Study First Posted: 2022-04-01
• Primary Completion: 2022-06-15
• Study Completion: 2022-07-06
• Last Update Submitted: 2022-07-19
• Last Update Posted: 2022-07-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Patients aged 20-55 years who were diagnosed with tarsal tunnel syndrome by electromyography (EMG) in the last 6 months were included in the study.

Exclusion Criteria

• Have a systemic inflammatory disease
• Presence of a cognitive disorder, receiving psychotherapy or any psychiatric treatment, disease affecting the central nervous system
• Being illiterate
• Having hearing, vision problems
• History of foot and ankle surgery
• Any pathology that may cause pain in the foot joint diagnosed on physical examination
• Inadequate function of any extremity that would prevent exercise
• The presence of a balance disorder or a disease that can disrupt the balance
• Diagnosis of advanced cardiac or lung disease for which exercise would be contraindicated

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Nerve Mobilization Group	Tibial Nerve Mobilization	Tibial nerve mobilization in addition to foot-ankle joint range of motion exercises
Control group	Foot-ankle range of motion exercises	Only joint range of motion exercises
Nerve Mobilization Group	Foot-ankle range of motion exercises	Tibial nerve mobilization in addition to foot-ankle joint range of motion exercises

Primary Outcome Measures

Name	Time	Method
Tinel's Sign	Change from Baseline at 4th weeks	It is performed by lightly tapping (percussing) over the nerve to elicit a sensation of tingling or "pins and needles" in the distribution of the Tibial nerve. The Tinel sign is the tingling or prickling sensation elicited by the percussion of an injured nerve trunk at or distal to the site of the lesion. The test is positive when a tingling or prickling sensation is felt in the distribution of the Tibial nerve.
Visual analogue scale	Change from Baseline at 4th weeks	VAS, a scale consisting of a single line of 10 cm, was used to evaluate pain severity.
Evaluation of the tibial nerve with ultrasonography	Change from Baseline at 4th weeks	Bilateral tibial nerve US evaluation using a 6-18 Mhz linear probe (Mindray-UMT 200, USA) will be performed by another clinician experienced in musculoskeletal ultrasonography and blind to the clinical evaluation findings of patients.

Secondary Outcome Measures

Name	Time	Method
Foot Function Index	Change from Baseline at 4th weeks	The severity of foot pain was scored with 23 items measuring the degree of difficulty in performing various functional activities due to foot problems and activity limitations due to foot problems. Turkish validity and reliability of the questionnaire was determined by Yalıman et al.
Neuropathic pain questionnaire	Change from Baseline at 4th weeks	Neuropathic pain questionnaire consists of 12 questions. Of the 12 questions, 10 are related to the character of the pain while two questions are related to sensitivity changes.

Trial Locations

Locations (1)

Kutahya Health Sciences University; 🇹🇷 Kütahya, Turkey