Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
Not Applicable
Not yet recruiting
- Conditions
- Mood Disturbance
- Registration Number
- NCT06531863
- Lead Sponsor
- Auburn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Inclusion Criteria:<br><br> - Adults age 18-50<br><br> - Depression score of >13/21 on the DASS-21 indicating moderate severity<br><br> - No change in medications or supplements over the past 3 months<br><br> - Can read and speak English<br><br>Exclusion Criteria:<br><br> - Currently consume curcumin or green tea daily<br><br> - Currently, pregnant, nursing, or trying to become pregnant<br><br> - Currently diagnosed with a perimenopausal disorder
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in total distress as measured via DASS-21 total score.;Changes in serum brain derived neurotrophic factor (BDNF).
- Secondary Outcome Measures
Name Time Method Changes in DASS-21 subscales (depression, anxiety, stress).;Changes in subjective sleep quality.;Changes in subjective physical activity.;Changes in diet quality.;Number of Participants who report daily adherence to supplementation intake;Changes in fasting alanine aminotransferase (ALT);Changes in fasting aspartate aminotransferase (AST)