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Clinical Trials/IRCT20100209003320N15
IRCT20100209003320N15
Completed
未知

The effects of a weight loss diet with or without prebiotic supplementation on anthropometric measures, metabolic and inflammatory status, gut permeability, endotoxemia and depression status in obese women with major depression disorder

Tabriz University of Medical Sciences0 sites48 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Tabriz University of Medical Sciences
Enrollment
48
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional
Sex
Female

Investigators

Eligibility Criteria

Inclusion Criteria

  • Non\-menopausal women aged 20\-50 years
  • Body Mass Index (BMI) range: 30\-40 Kg/m2
  • Suffering from mild to moderate depression based on DSM\-V (Diagnostic and Statistical Manual of Mental Disorders, 5th Edition) criteria, as diagnosed by a psychiatrist
  • willingness to participate in the study

Exclusion Criteria

  • Pregnancy or lactation
  • Co\-morbidity with other major psychological or neurological diseases including psychosis, multiple sclerosis (MS), bipolar disorder
  • Suffering from thyroid dysfunctions
  • A history of following particular diets
  • Using synthetic or herbal drugs for weight loss
  • Changes in type or dosage of any other medications or nutritional supplements, during the study
  • Using fiber supplements or taking more than 25 grams of dietary fiber per day
  • Regular use of prebiotic or probiotic products or supplements, or antibiotic drugs during 2 months prior to the study or during the study
  • Any significant events during the study, which might affect the patient's psychological health

Outcomes

Primary Outcomes

Not specified

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