Functional Outcomes Following Limb Sparing Surgery for Sarcoma Patients

Withdrawn

• Conditions: Sarcoma

• Registration Number: NCT00508339
• Lead Sponsor: M.D. Anderson Cancer Center

Brief Summary

Primary Objectives:

1. To classify the types of wound healing complications that occur after pre-operative radiation therapy and limb sparing resection for the treatment of soft tissue sarcomas of the extremity.

2. To evaluate the impact of each complication type on patient function and quality of life using the Toronto Extremity Salvage Score (TESS).

Detailed Description

Not available

Study Timeline

• Study Start: 2006-09
• Study First Submitted: 2007-07-26
• Study First Submitted QC: 2007-07-26
• Study First Posted: 2007-07-27
• Primary Completion: 2007-10
• Study Completion: 2007-10
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-31
• Last Update Posted: 2012-08-01

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Diagnosis of soft tissue sarcoma with histopathologic confirmation.
2. Treatment protocol that includes pre-operative radiation therapy.
3. Treatment protocol that includes limb-sparing surgical resection.
4. Patient has received MD Anderson Cancer Center multidisciplinary care.
5. Patient must be at least three years post-operative.

Exclusion Criteria

1. Previous radiotherapy to the local site.
2. Presence of regional or distant metastases.
3. Major medical co-morbidities (eg. cerebrovascular accident, congestive heart failure, concurrent malignancy) or disabilities unrelated to treatment for soft tissue sarcoma.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Endpoints for this study will be anatomic site, histological subtype, primary wound closure, wound complication type, need for secondary operation and type of secondary operation.	1 Year

Trial Locations

Locations (1)

U.T.M.D. Anderson Cancer Center; 🇺🇸 Houston, Texas, United States