CTRI/2022/09/045859尚未招募不适用
Does measurement of biomarker like suPAR (soluble urokinase plasminogen activated receptor) help reduce mortality in Type 2 diabetes mellitus patients undergoing Coronary artery bypass grafting (CABG) ?
All India Institute of Medical SciencesNew Delhi1 个研究点 分布在 1 个国家目标入组 96 人开始时间: 2022年9月30日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 96
- 试验地点
- 1
- 主要终点
- •To evaluate whether measurement of suPAR levels help in prognostication in patients with Type 2 Diabetes Mellitus undergoing CABG surgery
研究概览
简要总结
There have been several biomarkers searched in the past to predict cardiac injury and their role in the prognosis of the patients after cardiac event. We are also measuring different biomarkers in On Pump CABG patients and looking for their prognostic significance.The purpose of the study is to establish definite relationship between the rise of new cardiac biomarker soluble urokinase plasminogen activated receptor and its role in prgonosis of Type 2 diabetes melittus patients undergoing on pump CABG.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •1At least 18 years of age or older 2Known case of T2DM 3American Society of Anesthesiologists (ASA) physical status I to IV.
排除标准
- •1Patients below 18 years of age 2Patients undergoing another procedure alongwith CABG 3Redo cardiac surgery, redo CABG 4Emergency CABG , Off- pump CABG 5Patients with an active ongoing infection •Patients on cancer therapy •Severe liver disease •Allergies •Connective tissue disorders •Alcohol or other abuse •Refusal of consent for participation.
结局指标
主要结局
•To evaluate whether measurement of suPAR levels help in prognostication in patients with Type 2 Diabetes Mellitus undergoing CABG surgery
时间窗: 24 hours and 48 hours
次要结局
- 1.Duration of mechanical ventilation(2.Length of ICU stay)
研究者
研究点 (1)
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