Comparison of Pre-hospital and In-hospital Iv-tPA Stroke Treatment

Completed

• Conditions: Ischemic Stroke

• Registration Number: NCT02358772
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

This is a comparison of clinical outcomes between a pre-hospital and an in-hospital thrombolysis patient registry.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02
• Study First Submitted: 2015-02-04
• Study First Submitted QC: 2015-02-06
• Study First Posted: 2015-02-09
• Primary Completion: 2015-06
• Study Completion: 2016-07
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-08
• Last Update Posted: 2016-08-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 658

Inclusion Criteria

• Acute ischemic stroke diagnosis with thrombolytic treatment
• Admission via EMS
• Known premorbid status of need of assistance
• NIHSS before treatment available
• Time of onset (or last well seen) between 4:00am and 10:30pm

Exclusion Criteria

• Unknown time of onset
• In-hospital thrombolysis despite decision against treatment because of contraindications in STEMO

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
modified Rankin Scale (mRS) score	three months after event	dichotomized mRS 0-1 and 2-6 in patients who lived at home without assistance prior to the index stroke.

Secondary Outcome Measures

Name	Time	Method
modified Rankin Scale (mRS) score	three months after event	ordinal analysis across whole mRS range

Trial Locations

Locations (1)

Charité; 🇩🇪 Berlin, Germany