Relationship of Retinal and Visual Cortex Structure and Visual Acuity After Congenital Cataract Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Congenital Cataract
- Sponsor
- Wenzhou Medical University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Macular thickness
- Last Updated
- 4 years ago
Overview
Brief Summary
To evaluate the influence of the visual acuity after congenital surgery on the retinal and visual cortex structure.
Detailed Description
According to the visual acuity after congenital cataract surgery, 30 patients are divided into 3 groups.SD-OCT and MRI were used to measure the parameters of the retina and the visual cortex, to compare the differences between different groups, and to analyze the relationship between the structure of the retina and the visual cortex and visual acuity.
Investigators
Yune Zhao
Vice president of Eye Hospital of Wenzhou Medical University
Wenzhou Medical University
Eligibility Criteria
Inclusion Criteria
- •age of 4-60 years
- •Congenital cataract surgery is planned
- •The operation was successful without any complications
- •Can cooperate well with OCT and MRI examinations
Exclusion Criteria
- •Intraoperative and postoperative complications include glaucoma, retinal, corneal, or refractive medium diseases
- •Behavioral, cognitive impairment
- •Developmental delay
Outcomes
Primary Outcomes
Macular thickness
Time Frame: 2021.12.30
Scan the 3.0mm diameter ETDRS ring area in the macular area with SD-OCT.
Subfoveal choroidal thickness
Time Frame: 2021.12.30
Scan the Subfoveal choroid in enhanced scan mode with SD-OCT.
Retinal nerve fiber layer thickness
Time Frame: 2021.12.30
Scan concentric circles with a length of 3.4mm and a diameter ranging from 2.5mm to 4.0mm in 12 directions centered on the optic disc with SD-OCT.
The volume of the lateral geniculate body
Time Frame: 2021.12.30
Measure the volume of the lateral geniculate body by T1 phase scan of MRI
The volume of the brodmann 17,18,19 area
Time Frame: 2021.12.30
Masure the volume of the brodmann 17,18,19 area by T1 phase scan of MRI
The FA of the white matter fiber bundle
Time Frame: 2021.12.30
Measure the Fraction Anisotropy of the white matter fiber bundle related to visual signal transduction by DWI scan of MRI