Neurophysiological Correlates of Dissociation Induced by Virtual Reality Hypnosis (VRH) in an Oncological Population
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 主要终点
- Dissociation state
研究概览
简要总结
Hypnosis and virtual reality are potential tools for treating acute. Nevertheless, the neurophysiological correlates of such tools used together, i.e. 'virtual reality hypnosis' (VRH) (Patterson et al., 2004) remain mostly understudied. This study aims to improve our knowledge and understanding of the dissociation (i.e., a mental separation of components of behaviours that normally would be processed together) occurring during VRH. This is a clinical trial aiming at understanding if the VRH reduces pain during a port-a-cath intervention in oncological patients and if dissociation may explain the pain alteration.
详细描述
The study will be focused on oncological patients undergoing a port-a-cath placement procedure. Day-1 and Day-2 with a one-day follow-up Day-3:
I. Day-1: Oncological Population (Feasibility)
- Recruitment and questionnaires on the day of the port-a-cath preparation consultation (DAY-1): i. A medical screening will be performed to assess eligibility, ii. Elkins Hypnotizability Scale. iii. State Trait Anxiety Inventory-trait (anxiety trait) iv. Dissociative Experience Scale. v. Tellegen Absorption Scale. vi. Questionnaire of Immersion Propensity.
II. Day-2:
- Intervention day:
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
盲法说明
Methodology of virtual reality hypnosis prevents masking participants and experimenter.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subject more than 18 years old
排除标准
- •Low auditory and/or visual acuity precludes the use of the device.
- •Head or face wounds precluding the use of the device.
- •Schizophrenia, dissociative disorder or any other psychiatric disorder.
- •Non-proficiency in French (Research language).
- •Patient under 18 years old.
- •Phobia of deep water.
- •Allergy to cutaneous electrodes.
- •Chronic pain and/or chronic analgesics consumption.
- •Medication affecting the autonomic nervous system.
结局指标
主要结局
Dissociation state
时间窗: During the procedure
Corresponds to a dissociation between the bodily sensations and the actual environment that one feels in a particular situation. will be assessed with a numerical rating scale (0= no dissociation; 10 = dissociation from environment).
Pain intensity
时间窗: During the procedure
The amount of pain one experiences in a particular situation. Will be assessed with a visual analogy scale, 0= no pain at all; 10= worst pain imaginable.
次要结局
- Absorption trait(During the procedure)
- Anxiety state(During the procedure)
- Absorption state(During the procedure)
- Time perception(During the procedure)
- Cybersickness(During the procedure)
- Satisfaction of the participant(During the procedure)
- Arousal/wakefulness(During the procedure)
- Dissociation trait(During the procedure)
- Hypnotisability(During the procedure)
- Automaticity(During the procedure)
- Presence(During the procedure)
- Anxiety trait(During the procedure)
- Immersion propensity (trait)(During the procedure)
- Brief Pain Inventory(One week after the procedure)
研究者
Audrey Vanhaudenhuyse
PhD, head of the Perception and Sensation Research Group - GIGA Consciousness
University of Liege