Quality of Life in Postmenopausal Women Who Are Receiving Either Exemestane or Anastrozole With or Without Celecoxib for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
- Conditions
- Breast Cancer
- Registration Number
- NCT00090974
- Lead Sponsor
- Eastern Cooperative Oncology Group
- Brief Summary
RATIONALE: Quality-of-life assessment in postmenopausal women who are receiving hormone therapy for breast cancer may help to determine the effects of treatment on these patients and may improve the quality of life for future breast cancer patients.
PURPOSE: This clinical trial is studying quality of life of postmenopausal women who are receiving either exemestane or anastrozole with or without celecoxib for stage I, stage II, or stage IIIA primary breast cancer.
- Detailed Description
OBJECTIVES:
Primary
* Compare treatment-related symptoms using the Functional Assessment of Cancer Therapy-Endocrine Symptoms (FACT-ES) questionnaire in postmenopausal women with receptor-positive stage I, II, or IIIA primary breast cancer undergoing treatment with exemestane vs anastrozole with or without celecoxib on protocol CAN-NCIC-MA27.
Secondary
* Compare health-related quality of life using the FACT-ES questionnaire in patients treated with these regimens.
* Determine the extent to which differences in treatment-emergent symptoms affect overall quality of life in patients treated with these regimens.
OUTLINE: This is a multicenter, companion study. Patients receive treatment on CAN-NCIC-MA27.
Health-related quality of life and treatment-related symptoms are assessed using the Functional Assessment of Cancer Therapy-Endocrine Symptoms (FACT-ES) questionnaire at baseline and at 3, 6, 12, and 24 months.
PROJECTED ACCRUAL: A total of 1,253 patients will be accrued for this study.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- Not specified
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (224)
Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital
🇺🇸Fairbanks, Alaska, United States
Banner Good Samaritan Medical Center
🇺🇸Phoenix, Arizona, United States
CCOP - Western Regional, Arizona
🇺🇸Phoenix, Arizona, United States
Banner Thunderbird Medical Center
🇺🇸Phoenix, Arizona, United States
North Bay Cancer Center
🇺🇸Fairfield, California, United States
Glendale Memorial Hospital Comprehensive Cancer Center
🇺🇸Glendale, California, United States
Memorial Medical Center Cancer Services
🇺🇸Modesto, California, United States
Comprehensive Cancer Center at Desert Regional Medical Center
🇺🇸Palm Springs, California, United States
Front Range Cancer Specialists
🇺🇸Fort Collins, Colorado, United States
Poudre Valley Hospital
🇺🇸Fort Collins, Colorado, United States
Scroll for more (214 remaining)Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital🇺🇸Fairbanks, Alaska, United States