Effect of Stellate Ganglion Block on Meniere's Disease
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- SP/AP of Electrocochleography
研究概览
简要总结
Stellate ganglion block (SGB) has been the alternative treatment of Meniere's disease for years. However, objective evidence of the effect of SGB was still lack. The investigators conducted a randomized controlled study to examine the immediate effects of SGB in SP/AP of electrocochleography (ECoG).
详细描述
Ten patients were randomly assigned to receive stellate ganglion block. These ten patients made up the experimental group. Another ten patients in the control group were assigned to receiving one dosage of oral medications: 0.25mg of erispan@ (fludiazine) , 25mg cephadol@ (diphenidol), and 200mg kentons@ (tocopherol nicotinate).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed with unilateral Meniere's disease, according to the criteria of the American Academy of Otolaryngology-Head and Neck Surgery, AAO-HNS (1995)
排除标准
- •patients with coagulopathy,
- •arrhythmia,
- •myocardial ischemia,
- •glaucoma,
- •pregnant,
- •chronic otitis media or externa, and
- •past history of middle or inner ear surgery were excluded.
研究组 & 干预措施
Stellate ganglion block
treated with SGB
干预措施: stellate ganglion block (Procedure)
Oral medication
treated with oral medications: 0.25mg of erispan@ (fludiazine) , 25mg cephadol@ (diphenidol), and 200mg kentons@ (tocopherol nicotinate).
干预措施: 0.25mg, fludiazine (Drug)
Oral medication
treated with oral medications: 0.25mg of erispan@ (fludiazine) , 25mg cephadol@ (diphenidol), and 200mg kentons@ (tocopherol nicotinate).
干预措施: 25mg cephadol@ (diphenidol) (Drug)
Oral medication
treated with oral medications: 0.25mg of erispan@ (fludiazine) , 25mg cephadol@ (diphenidol), and 200mg kentons@ (tocopherol nicotinate).
干预措施: 200mg kentons@ (tocopherol nicotinate). (Drug)
结局指标
主要结局
SP/AP of Electrocochleography
时间窗: ECoG was reorded 2 hours after SGB
SP/AP of ECoG was recorded 2 hours after SGB. to be compared with the SP/AP of ECoG recorded before treatment
次要结局
- SP/AP recorded at 4 hours after SGB(4 hours after SGB)
- SP/AP recorded at 6 hours after SGB(6 hours after SGB)
- scores of verbal scale for vertigo recorded at 6 hours after SGB(6 hours after SGB)
研究者
Yung-Song Lin
Chairman of department of Otolaryngology
Chi Mei Medical Hospital