Comparison of chemotherapy before and after definitive chemotherapy-radiotherapy with definitive chemotherapy-radiotherapy alone in patients with advanced cervical cancer

Phase 2

• Conditions: Cancer of cervix.; Malignant neoplasm of endocervix; C53.0

• Registration Number: IRCT20211011052730N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 35

Inclusion Criteria

Patients with advanced cervical cancer (FIGO Ib3-II-III-IVA)

Exclusion Criteria

Previous treatment with neoadjuvant chemotherapy
History of previous surgical treatment
History of radiotherapy in the pelvis and abdomen

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Disease free survival. Timepoint: One year and two year after intervention. Method of measurement: Physical exam and pelvic MRI.;Improved treatment response. Timepoint: One year and two year after intervention. Method of measurement: Physical exam and pelvic MRI.;Reduction of radiation therapy-related side effects. Timepoint: One year and two year after intervention. Method of measurement: History and Physical exam and pelvic MRI.