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THE EFFECT OF GENETIC AND EPIGENETIC DISPOZITIONS ON THE EFFICIENCY AND SAFETY OF OLANZAPINE PSYCHOSIS THERAPY

Phase 1
Conditions
Psychoses
Therapeutic area: Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04]
Registration Number
EUCTR2018-002267-25-CZ
Lead Sponsor
Fakultní nemocnice Brno
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

1. Dg. F20, F25 according to ICD-10 , treated with olanzapine or initiated treatment by olanzapine
2. Age 18-60 years
3. Signing the informed consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 200
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1. Involuntary hospitalization
2. Sui juris restriction or divestiture
3. Olanzapine or caffeine contraindication
4. Pregnancy or breastfeeding
5. Disagreement with the required contraception method(s)
6. Prior participation in any other trial involving investigational medication or medical devices within 14 days prior to the enrolment and during this trial;
7. Other serious medical or psychiatric illness that is not adequately controlled and, in the Investigator’s opinion, would not permit the subject to be managed according to the protocol.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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