role of steroids in preventing tubercular intestinal stricture
Not Applicable
- Conditions
- Health Condition 1: A183- Tuberculosis of intestines, peritoneum and mesenteric glands
- Registration Number
- CTRI/2020/01/022698
- Lead Sponsor
- G B Pant Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Proven ileo-colonic tuberculosis and
2.Proven stricture with radiographic and/or endoscopic evidence and
3. Symptomatic for stricture
Exclusion Criteria
1.Age <18 and >75 years
2.Coexisting HIV, Malignancy, Pregnancy
3.Past history of abdominal tuberculosis
4. Past abdominal surgery
5. Coexisting inflammatory bowel disease
6.Contraindications for steroid use like osteoporosis, glaucoma, uncontrolled diabetes, uncontrolled ongoing sepsis, excess fluid retention like congestive heart failure, renal failure, cirrhosis with ascites
7. Post-surgical diagnosis of tuberculosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method improvement in stricture either by colonoscopy or by CECT enterographyTimepoint: Outcome assessed after 6 months
- Secondary Outcome Measures
Name Time Method 1. Symptoms improvement in form of Pain reduction, Weight gain <br/ ><br>2 No of hospital admissions for pain <br/ ><br>3. requirement of surgery <br/ ><br>4.MortalityTimepoint: At 2months and at 6 months