Pneumococcal conjugate vaccine trial: PNEUVAC TRIA
Completed
- Conditions
- Invasive pneumococcal disease in HIV-infected AfricansInfections and InfestationsInvasive pneumococcal disease
- Registration Number
- ISRCTN54494731
- Lead Sponsor
- niversity of Liverpool (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 320
Inclusion Criteria
1. Confirmed case of IPD discharged from hospital
2. Resident of Blantyre and its immediately neighbouring districts
3. Willing to attend Queen Elizabeth Central Hospital (QECH) when sick
4. Aged over 15 years, either sex
5. Willing to have HIV testing performed on stored serum
Exclusion Criteria
1. Pregnancy
2. Previous pneumococcal vaccine
3. Active acute systemic illness - following recovery participant may be recruited
4. Past hypersensitivity reaction to vaccination
5. Bed-ridden or life expectancy judged to be less than three months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vaccine serotype invasive pneumococcal disease
- Secondary Outcome Measures
Name Time Method 1. All invasive pneumococcal disease death<br>2. All cause pneumonia