Investigation of Pectoralis Muscle Strength in Elderly With Interstitial Lung Disease

Completed

• Conditions: Interstitial Lung Disease; Sarcoidosis, Pulmonary; Geriatric; Idiopathic Pulmonary Fibrosis
• Interventions: Other: Assessment of pulmonary function and pectoralis muscle strength

• Registration Number: NCT04803617
• Lead Sponsor: Habibedurdu

Brief Summary

Interstitial lung disease (ILD) is a restrictive lung disease characterized by impaired lung function, exercise limitation and skeletal muscle dysfunction. There is limited data on skeletal muscle function in ILD, most of which are focused on the lower limb muscles. The aim of this study were to evaluated the change of pectoralis muscle strength and relationship of pulmonary function with pectoralis muscle strength.

Detailed Description

This study consisted of intervention and control groups. Thirty one patients with ILD were included in the patient's group and 37 healthy volunteers in the control group. All participants were selected from the geriatric population. Demographic and cardiopulmonary physiotherapy assessment of all participants were performed. Lung function test, maximal inspiratory and expiratory pressure and pectoralis muscle strength were measured in participants of both groups. All measurements were performed once.

Study Timeline

• Study Start: 2017-01-23
• Primary Completion: 2017-06-23
• Study Completion: 2017-06-23
• Status Verified: 2021-03
• Study First Submitted: 2021-03-13
• Study First Submitted QC: 2021-03-16
• Last Update Submitted: 2021-03-16
• Study First Posted: 2021-03-17
• Last Update Posted: 2021-03-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• Diagnosed with ILD by a multidisciplinary team according to the 2011 ATS/ERS guidelines for ILD
• Aged 65-85

Exclusion Criteria

• Uncontrolled/active cardiovascular, metabolic, systemic or cancerous disease
• Significant orthopedic, neurologic or musculoskeletal comorbidity that limited functional independence
• No being able to cooperate
• Refuse to participate in the current study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control group	Assessment of pulmonary function and pectoralis muscle strength	healthy volunteers selected from the geriatric population
Patient's group	Assessment of pulmonary function and pectoralis muscle strength	geriatric patients with interstitial lung disease

Primary Outcome Measures

Name	Time	Method
Pectoralis muscle strength test	15 minute	The pectoralis muscle strength were measured with handheld dynamometer in supine position. The shoulder joint of participant was positioned at 90º abducted and at 0º internal/external rotation and the elbow joint was flexed at 90º. The other shoulder joint was fixed by the physiotherapist. While the participant performed isometrically horizontal adduction movement, the measurement was performed on the distal part of the upper arm and the contraction was sustained for at least 5 seconds by the participant. The test was performed three times and with 60 seconds rest between tests. The mean of the best value on both sides was recorded.

Secondary Outcome Measures

Name	Time	Method
FVC	5 minute	FVC value was measured with portable spirometer according to ATS/ ERS guidelines for pulmonary function test. Results of the measurements were recorded as percentanges of predicted values.
Respiratory muscle strength test	15 minute	Maximal mouth pressures were measured to evaluate respiratory muscle strength. The test was performed with mouth pressure device in sitting position. Participants breathed through a flanged mouthpiece inside the lips at near residual volume for the MIP value and near total lung capacity for MEP value . The maximum effort was sustained for at least one second. The test was repeated at least 3 times until no more than 10% difference was present between highest and previous measurements . The higest value and percentage value of predicted highest value were recorded
FEV1/FVC	5 minute	The ratio of FEV1/FVC was calculated by measuring device according to measured FEV1 and FVC values
Dyspnea assessment	3 minute	Modified Medical Council Research Dyspnea scale were used to assess sensation of dyspnea
FEV1	5 minute	FEV1 value was measured with portable spirometer according to ATS/ ERS guidelines for pulmonary function test. Results of the measurements were recorded as percentanges of predicted values.

Trial Locations

Locations (1)

Giresun University; 🇹🇷 Giresun, Turkey