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临床试验/NCT03874624
NCT03874624Unknown不适用

Normal Values for Myocardial Left Atrial Strain

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau1 个研究点 分布在 1 个国家目标入组 43 人开始时间: 2019年2月22日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
43
试验地点
1
主要终点
Global peak reservoir strain.

研究概览

简要总结

Transversal retrospective and unicentric study. The investigators sought to determine the normal values for two-dimensional myocardial left atrial strain for the cardiology ultrasound system available in their centre (Philips EPIQ ultrasound machine and 10.8.5 QLAB cardiac analysis software). Studies performed in their department which meet the criteria for an adequate strain analysis will be retrospectively reviewed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • No history of cardiopathy / pneumopathy.
  • No history of hypertension or mellitus diabetes.

排除标准

  • Pregnancy.
  • Athletes.
  • Body mass index < 16 or => 30 kg/m
  • Previous treatment with cardiotoxic chemotherapy.
  • Dilated left ventricle (telediastolic diameter index > 30 mm/m2).
  • Interventricular septal thickness => 12 mm.
  • Dilated left atria (volume => 31 ml/m2).
  • Systolic pulmonary pressure => 35 mmHg.
  • Moderate or severe valvulopathy.
  • Incomplete or suboptimal left atrial visualization.
  • Frame rate < 50 fps.

结局指标

主要结局

Global peak reservoir strain.

时间窗: Through study completion, an average of 4 months.

Percentage of peak reservoir strain for 4-, 2- and 3-chambers will be combined to report percentage of global peak reservoir strain.

Global pump strain.

时间窗: Through study completion, an average of 4 months.

Percentage of pump reservoir strain for 4-, 2- and 3-chambers will be combined to report percentage of global pump strain.

Global conductance strain.

时间窗: Through study completion, an average of 4 months.

Measured as the difference between global reservoir strain and gobal pump strain.

Global reservoir strain rate.

时间窗: Through study completion, an average of 4 months.

Reservoir strain rate for 4-, 2- and 3-chambers will be combined to report global reservoir strain rate.

Global conductance strain rate.

时间窗: Through study completion, an average of 4 months.

Conductance strain rate for 4-, 2- and 3-chambers will be combined to report global conductance strain rate.

Global pump strain rate.

时间窗: Through study completion, an average of 4 months.

Pump strain rate for 4-, 2- and 3-chambers will be combined to report global pump strain rate.

次要结局

  • Sex(Through study completion, an average of 4 months.)
  • Weight in kilograms(Through study completion, an average of 4 months.)
  • Age in years(Through study completion, an average of 4 months.)
  • Height in meters(Through study completion, an average of 4 months.)
  • Left atrial volume(Through study completion, an average of 4 months.)
  • Left ventricular ejection fraction(Through study completion, an average of 4 months.)
  • Left ventricular telediastolic volume(Through study completion, an average of 4 months.)
  • Left ventricular dimensions(Through study completion, an average of 4 months.)
  • E/A ratio(Through study completion, an average of 4 months.)
  • E/e' ratio(Through study completion, an average of 4 months.)

研究者

发起方
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
申办方类型
Other
责任方
Sponsor

研究点 (1)

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