NCT06353659尚未招募不适用
The Diagnostic Value of Contrast-enhanced Ultrasound in Acute Kidney Injury in Intensive Care Unit
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 主要终点
- Acute kidney injury (according to KDIGO 2012 criteria)
研究概览
简要总结
The goal of this observational study is to quantitatively assess the renal microcirculation changes by contrast-enhanced ultrasound (CEUS) and to obtain systemic hemodynamic information by ultrasound Doppler at the same time, to analyze the relationship between renal microcirculation changes and systemic hemodynamic changes, and to explore the diagnostic value of CEUS in critically ill acute kidney injury.
详细描述
The main questions it aims to answer are:
- To explore the quantitative parameters of contrast-enhanced ultrasound which can reflect the changes of renal microcirculation。
- To explore the relationship between renal microcirculation and systemic hemodynamics。
- To explore the value of quantitative evaluation of renal microcirculation changes by contrast-enhanced ultrasound in the diagnosis of acute kidney injury
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age>18 years old
- •First admission to ICU < 24h after admission and expected ICU stay ≥48 hours
- •Acute kidney injury risk factors (KDIGO 2012)
- •Contrast-enhanced ultrasound
排除标准
- •Known severe chronic kidney disease (CKD≥ stage 4) or undergoing hemodialysis treatment
- •Kidney transplantation or renal malignancy
- •Terminal stage of malignant tumor
- •Pregnancy
- •Renal artery stenosis or renal vein thrombosis
- •The quality of CEUS images is poor, and quantitative analysis cannot be performed
结局指标
主要结局
Acute kidney injury (according to KDIGO 2012 criteria)
时间窗: Through study completion, an average of 7 days
Acute kidney injury occur or not
次要结局
未报告次要终点
研究者
Cui Ligang
Chief Physician
Peking University Third Hospital
相似试验
招募中
不适用
The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICUIntensive Care UnitUltrasoundAcute Kidney InjuryNCT06341062Peking University Third Hospital44
Unknown
不适用
Validation of Renal Perfusion CEUS Against MRI, and Its Application in Acute Kidney InjuryKidney Injury, AcutePerfusion ImagingUltrasonographyKidney DiseasesNCT04181281University of Nottingham50
Unknown
不适用
Contrast Ultrasound Assessment of Perfusion Changes After Peripheral Artery RevascularizationPeripheral Artery DiseaseNCT02877563Oregon Health and Science University30
Enrolling By Invitation
2 期
A Study of Renal Microvessel Imaging for Chronic Kidney DiseaseHealthyChronic Kidney DiseasesNCT05764642Mayo Clinic186
Unknown
不适用
Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast UltrasoundKidneyNCT00631553University of Virginia20