The Diagnostic Value of Contrast-enhanced Ultrasound in Acute Kidney Injury in Intensive Care Unit
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Intensive Care Unit
- Sponsor
- Peking University Third Hospital
- Enrollment
- 60
- Primary Endpoint
- Acute kidney injury (according to KDIGO 2012 criteria)
- Status
- Not Yet Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this observational study is to quantitatively assess the renal microcirculation changes by contrast-enhanced ultrasound (CEUS) and to obtain systemic hemodynamic information by ultrasound Doppler at the same time, to analyze the relationship between renal microcirculation changes and systemic hemodynamic changes, and to explore the diagnostic value of CEUS in critically ill acute kidney injury.
Detailed Description
The main questions it aims to answer are: 1. To explore the quantitative parameters of contrast-enhanced ultrasound which can reflect the changes of renal microcirculation。 2. To explore the relationship between renal microcirculation and systemic hemodynamics。 3. To explore the value of quantitative evaluation of renal microcirculation changes by contrast-enhanced ultrasound in the diagnosis of acute kidney injury
Investigators
Cui Ligang
Chief Physician
Peking University Third Hospital
Eligibility Criteria
Inclusion Criteria
- •Age\>18 years old
- •First admission to ICU \< 24h after admission and expected ICU stay ≥48 hours
- •Acute kidney injury risk factors (KDIGO 2012)
- •Contrast-enhanced ultrasound
Exclusion Criteria
- •Known severe chronic kidney disease (CKD≥ stage 4) or undergoing hemodialysis treatment
- •Kidney transplantation or renal malignancy
- •Terminal stage of malignant tumor
- •Pregnancy
- •Renal artery stenosis or renal vein thrombosis
- •The quality of CEUS images is poor, and quantitative analysis cannot be performed
Outcomes
Primary Outcomes
Acute kidney injury (according to KDIGO 2012 criteria)
Time Frame: Through study completion, an average of 7 days
Acute kidney injury occur or not