Evaluation of the Effectiveness of Predicting the Integrity of Interlobar Fissures Based on Chest Image AI Technology
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease
- Sponsor
- China-Japan Friendship Hospital
- Enrollment
- 40
- Primary Endpoint
- Therapeutic effect of lung volume reduction surgery
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
The goal of observational study is to evaluate effectiveness of predicting the integrity of interlobar fissures based on chest image AI technology in patients with Chronic Obstructive Pulmonary Disease who will undergo lung volume reduction surgery with endobronchial valve implantation. The main question it aims to answer is: evaluation of the effectiveness of predicting the integrity of interlobar fissures based on chest image AI technology.
Participants will be evaluated by lung CT (quantitative analysis based on chest image AI technology and artificial analysis) and imported Chartis detection system.
Investigators
Gang Hou
Principal Investigator
China-Japan Friendship Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients with chronic obstructive pulmonary disease who meet the GOLD diagnostic criteria
- •FEV1 ≤ 45% pred and FEV1/FVC\<70%
- •TLC\>100% pred and RV\>175% pred
- •\>50% of emphysema destruction
- •Smoking prohibition\>6 months
- •Sign the informed consent form
Exclusion Criteria
- •PaCO2\>8.0 kPa, or PaO2\<6.0 kPa
- •6-minute walking test\<160m
- •Obvious chronic bronchitis, bronchiectasis or other infectious lung diseases
- •Three hospitalizations due to pulmonary infection in the past 12 months before the baseline assessment
- •Previous lobectomy, LVRS or lung transplantation
- •LVEF\<45% and or RVSP\>50mmHg
- •Anticoagulant therapy that cannot be stopped before surgery
- •The patient has obvious immune deficiency
- •Participated in other lung drug studies within 30 days before this study
- •Pulmonary nodules requiring intervention
Outcomes
Primary Outcomes
Therapeutic effect of lung volume reduction surgery
Time Frame: 6 months after bronchoscopic valve lung volume reduction
Lung CT
the integrity of interlobar fissure
Time Frame: Before bronchoscopic valve lung volume reduction
Emphysema quantitative analysis softwarebased on chest image AI technology, artificial analysis and imported Chartis detection system