Yokohama Heart Failure Investigators:Time Zone Dynamics of Serum Arginine-Vasopressin and Urine Aquaporin-2 on Acute Decompensated Heart Failure in the Patients with Depressed Left Ventricular Functio
- Conditions
- Acute congestive heart failure
- Registration Number
- JPRN-UMIN000018717
- Lead Sponsor
- ational Hospital Organization Yokohama Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 16
Not provided
1)patient with acute heart failure presenting clinical scenarios 3, 4, and 5 2)patient to whom tolvaptan has already been administered 3)patient to whom continuous intravenous infusion inotropes (catecholamine, phosphodiesterase-3 inhibitors, colforsin daropate hydrochloride, etc) has already been administered or is planned to be administered 4)patient who has received mechanical support (invasive mechanical ventilation, intraaortic balloon pumping, percutaneous cardiopulmonary support, continuation hemofiltration-dialysis, etc.) or is planned to use it 5)patient who presents shock at enrollment 6)Patient with advanced renal dysfunction (eGFR<30ml/min/1.73m2) 7)patient who is judged to be improper by the doctor in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method urine volume per 6 hours
- Secondary Outcome Measures
Name Time Method Relationship between urine AQP2, serume AVP and diuresis effect of tolvaptan