Biomagnetic Signals of Intestinal Ischemia II
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 17
- Locations
- 1
- Primary Endpoint
- To observe a difference in the magnetic activity between the normal and diseased smooth muscle of the small intestine
Study Overview
Brief Summary
The lack of blood flow to the small intestine causes mesenteric ischemia. Using a Superconducting QUantum Interference Device (SQUID) which measures the magnetic field of the small intestine, we are hoping to identify abnormalities without surgical intervention.
Detailed Description
The electrical activity of the small intestine may contain important information that will help us diagnose gastrointestinal diseases. The major impediment to reducing mortality of mesenteric ischemia is the lack of a noninvasive diagnostic test that identifies the syndrome before extensive necrosis occurs. Mesenteric ischemia is caused by the lack of blood flow to the intestine. The Superconducting QUantum Interference Device (SQUID) measures the magnetic field of the intestinal smooth muscle. By comparing normal smooth muscle and that of patients with mesenteric ischemia, the investigators hope to identify abnormal disease states without surgery.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Normal subjects and those with diagnosed mesenteric ischemia
Exclusion Criteria
- •Subjects who report a tendency toward claustrophobia
Outcomes
Primary Outcomes
To observe a difference in the magnetic activity between the normal and diseased smooth muscle of the small intestine
Time Frame: 2010
Secondary Outcomes
- Create mathematical and computer models of electrical activity of smooth muscle(2010)
Investigators
Alan Bradshaw
Research Assistant Professor
Vanderbilt University Medical Center