Healthcare-associated Infections in Severe COVID-19 Patients Whit Mechanical Ventilation During 2020
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 252
- Locations
- 1
- Primary Endpoint
- Incidence of health care associated infections in each group.
Study Overview
Brief Summary
In patients who develop ARDS due to SARS-CoV-2 (CARDS), a longer duration of invasive mechanical ventilation (IMV) and ICU stay has been reported compared to ARDS not associated with SARS-CoV-2. Consequently, the days of stay in ICU increase Identifying the risk factors associated with the development of this complication and developing measures aimed at its prevention could have a favorable impact on the clinical course of seriously ill patients.
Detailed Description
The rate of catheter-associated bacteremia is 3.78 / 1000 days central venous catheters in polyvalent ICUs.
Some studies suggest that in the context of this pandemic, infections associated with health care have increased, although there are few data referring to Latin America.
The objective of this study is to analyze the incidence of health care associated infections in adult patients on invasive mechanical ventilation with confirmed COVID-19 diagnosis and negative COVID-19 admitted to the Intensive Care Unit of the Anchorena San Martín Clinic, San Martín, Buenos Aires.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All patients older than 18 years admitted to the intensive care unit of the Anchorena San Martín Clinic who required invasive mechanical ventilation for more than 24 hours in a period between March 2020 and December 2020 were included in the analysis.
Exclusion Criteria
- •All patients who presented incomplete data in the follow-up sheets were excluded.
Outcomes
Primary Outcomes
Incidence of health care associated infections in each group.
Time Frame: March to December 2020
Secondary Outcomes
- mortality in UCI(March to December 2020)
- Days of ICU stay(March to December 2020)
- Possible factors associated with Incidence of health care associated infections.(March to December 2020)
- Days of mechanical ventilation(March to December 2020)
- The most frequent pathogens in this population associated with Incidence of health care associated infections.(March to December 2020)
Investigators
Matias Accoce
RT
Sanatorio Anchorena San Martin