Outcome After Avascular Necrosis of the Femoral Head in Young Patients - Retrospective Analysis With a Min. 10-year Follow-up
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 主要终点
- rate of reoperations after THA
研究概览
简要总结
- The course of AVN between Initial diagnosis and total hip replacement (THA) is analysed. The impact of early interventions versus conservative therapy in AVN before THA will be evaluated.
- The short and long term outcomes of AVN patients undergoing THA with respect to complications, reoperations and quality of life are investigated. Potential risk factors for adverse outcomes will be investigated.
详细描述
The study is to describe the course of avascular necrosis (AVN) of the femoral head from initial diagnosis and to collect data on treatment options and the further course in these cases. The duration from initial diagnosis of AVN to joint replacement as total hip arthroplasty (THA) will be analysed and the course after joint replacement with potential short- and long-term complications will be evaluated.
The impact of THA after AVN on activities of daily living will be assessed by Euroquol 5 Dimensions (EQ-5D-5L) and Hip disability and Osteoarthritis Outcome Score (HOOS) questionnaires.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •MRI of the hip available from diagnosis at the USB or KSBL Liestal
- •Informed Consent
排除标准
- •Insufficient knowledge of project languages (English, German, French)
结局指标
主要结局
rate of reoperations after THA
时间窗: single time point assessment at baseline
reoperation after THA = time to event data (in the years between 2000-2007)
arthroplasty-free interval (time until THA)
时间窗: single time point assessment at baseline
time from first diagnosis of AVN to joint replacement = time to event data (in the years between 1999-2006)
次要结局
- Hip disability and Osteoarthritis Outcome Score (HOOS)(single time point assessment at baseline)
- Euroquol 5 Dimensions (EQ-5D-5L)(single time point assessment at baseline)