The effect of low dose ketamine on postoperative hyperalgesia
Not Applicable
Recruiting
- Conditions
- Diseases of the musculo-skeletal system and connective tissue
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
The patients who have degenerated osteoarthritis or rheumatoid arthritis who were included in ASA -PS(American society of anesthesiology- physical status) class I or II
Exclusion Criteria
the patients who are beyond ASA-PS(ASA -PS(American society of anesthesiology- physical status)class III
the patients who have the side effects of PCA(patient-controlled analgesia) including PONV(postoperative nausea and vomitting) history
the patients who have severe pain need to take pain killers before surgery (VAS>4)
The patients who have the criteria of ketamine contraindication
The pateints who have severe cardiac disease ( arrhythimia or valve disease)
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the difference of VAS(visual analoque scale) in first postoperative day after second total knee arthroplasty in each group respectively ;the difference in VAS(visual analoque scale) in first postoperative day between first and second leg postoperative pain in one patinet
- Secondary Outcome Measures
Name Time Method the difference of VAS(visual analoque scale) in second and third postoperative day, after second total knee arthroplasty, in each group respectively;the difference in VAS(visual analoque scale) in second and third postoperative day between first and second leg postoperative pain in one patinet