Occlusal function in orthognathic patients during therapy – a clinical prospective study
Phase 4
- Conditions
- K07.1K07.2Anomalies of jaw-cranial base relationshipAnomalies of dental arch relationship
- Registration Number
- DRKS00025729
- Lead Sponsor
- niversitätsmedizin Göttingen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 51
Inclusion Criteria
The inclusion criteria were severe skeletal anomaly (prognathous/retrognathous maxilla and/or mandible) with characteristic dental manifestations in the form of elevated or inverse overbite, open bite, deep bite.
Exclusion Criteria
Exclusion criteria were an underlying congenital syndrome, a history of cleft lip and palate, a history of trauma, or patients who had been previously treated with osteotomy of the maxilla/lower jaw.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quantitative analysis of masticatory efficiency using digital occlusion measuring instrument before and after therapy
- Secondary Outcome Measures
Name Time Method Evaluation of the therapeutic effects taking into account the original jaw malposition and performed intervention after completion of therapy
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How do molecular pathways like BMP or FGF signaling influence occlusal function in orthognathic patients with K07.1/K07.2 anomalies during therapy?
What is the comparative effectiveness of orthognathic surgical techniques versus non-surgical interventions for correcting K07.2 dental arch relationship anomalies?
Which genetic biomarkers predict long-term occlusal stability in patients with jaw-cranial base relationship anomalies (K07.1) undergoing orthognathic treatment?
What adverse events are commonly reported in phase IV orthognathic trials, and how are temporomandibular joint complications managed post-surgery?
How do combination therapies involving orthognathic surgery and biomechanical modeling improve masticatory efficiency in K07.2 dental arch relationship anomaly patients?