Transepithelial photorefractive keratectomy : A randomized comparative study between two-step and one-step techniques of transepithelial PRK and the rate of wound healing with different lubricating eye drops.
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- visual acuity
研究概览
简要总结
To find if there is any difference in the 1 month post -op visual outcome between the eyes which have undergone two step t-PRK vs single step t-PRK.
Rate of corneal epithelial wound( created by the t-PRK) healing using 3 different lubricating eye drops with varying composition
-
PLAIN SODIUM HYALURONATE 0.1%
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POLYETHYLENE GLYCOL 0.4% w/v, PROPYLENE GLYCOL 0.3% w/v, SODIUM PERBORATE 0.028% w/v, HYDROXYPROPYL GUAR GUM
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SODIUM HYALURONATE 0.15% w/v, POLYETHYLENE GLYCOL 0.3% w/v, PROPYLENE GLYCOL 0.3% w/v, HYDROXYPROPYL GUAR
Area will be calculated using an app called SketchAndCalc.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- All
入选标准
- •People who have myopic astigmatism with a spherical error between -1 to -6 diopters and a cylindrical error between -0.5 to -4 diopters.
- •People who have a stable refractive error at least for the past 1 year.
- •People who can come for a followup duration of at least 1 month.
- •Normal corneal tomography.
- •Minimum pachymetry of 470 micrometers.
排除标准
- •History of any previous corneal surgery.
- •Family history of keratoconus.
- •History of keloid tendency.
- •Pregnant,lactating women( upto 6 months of delivery).
- •If the person has keratitis or corneal scar.
- •Any corneal dystrophies.
- •Hyperopia.
结局指标
主要结局
visual acuity
时间窗: visual acuity on 1 and 3 months | rate of corneal epithelial wound healing on days 1,3,5 and 1 month
rate of corneal epithelial wound healing
时间窗: visual acuity on 1 and 3 months | rate of corneal epithelial wound healing on days 1,3,5 and 1 month
次要结局
- Pain & discomfort in eyes after surgery( t- PRK).
研究者
Ganthi Chetana Lakshmi
Sankara eye hospital, Pedakakani, Guntur