EFFICACY OF JANU PICHU, BRIMHANA SNEHAPANA AND MATRA BASTI WITH KSHEERABALA TAILA IN THE MANAGEMENT OF SANDHIGAT VATA (OSTEOARTHRITIS ); A COMPARATIVE CLINICAL STUDY
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.Reduction in Pain
研究概览
简要总结
INTRODUCTION**:**
Osteoarthritis is the most common type of arthritis in both developed and developing countries. It is a chronic, progressive musculoskeletal disorder characterized by gradual loss of cartilage in joints which results in bones rubbing together and creating stiffness, pain and impair movements. Osteoarthritis is strongly associated with ageing and is major cause of pain and disability in older people.The overall prevalence of knee Osteoarthritis was found to be 28.7% in India.
Sandhigatvata stands top among all Vatavyadhi in the list. The affliction of Sandhis (joints) by Prakupita Vata is the chief phenomena in Samprapti (aetiopathogenesis) of Sandhigatvata.
Osteoarthritis of knee joint can be compared with Janu Sandhigat Vata due to its clinical appearance and pathogenesis. Janu Sandhigat Vata is one among the most common Sandhigat Vata Vyadhi. This disease affects the knee joint which is one among the most important weight bearing joint in the body. In Ayurveda, Snehana (Oleation), Swedana (Sudation), Mridu Shodhana (mild cleansing treatment) are the prime modalities of treatment in the management of Vatavyadhi in general. Snehana and Swedana are specifically indicated for the treatment of *Sandhigat Vata.*Ksheerabala Taila has been mentioned by almost all ancient ayurvedic texts with different names and is a vatahara *taila.*Hence this study is planned to evaluate the effect of Janu Pichu, Brimhana Snehapana and Matra basti with ksheerabala taila in relieving pain in the patients of osteoarthritis of knee joint.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Open Label
入排标准
- 年龄范围
- 40.00 Year(s) 至 70.00 Year(s)（—）
入选标准
- •1.Age between 40-70 yrs.
- •2.Chronicity: 6 months to 10 yrs.
- •Gender :Both.
- •Socio-economic status: All 5.Degenerative changes in X- ray of knee joint (Grade 1, 2, 3) 6.Subjects fit for Basti Karma and Brimhana Snehapana.
排除标准
- •1.Subjects with Diabetes Mellitus 2.Subjects diagnosed with Rheumatoid Arthritis.
- •3.Subjects with infective arthritis.
- •4.Subjects unfit for Basti karma, Brimhana Snehapana.
- •5.Grade 4 in X ray finding of Knee Joint.
- •6.Subjects having BMI more than 30 7.Traumatic cases like fractures of Knee Joint.
结局指标
主要结局
1.Reduction in Pain
时间窗: (DAY-0)(DAY-13)(DAY-27)(DAY-34)(DAY-64)
2.Improvement in Range of Motion
时间窗: (DAY-0)(DAY-13)(DAY-27)(DAY-34)(DAY-64)
次要结局
- Reduction in symptoms like swelling, tenderness, crepitation, improvement in range of motion.