Effects of Yogic Breathing on Microvascular Endothelial Function and Symptoms in Participants With IBS
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Autonomic function
研究概览
简要总结
Adults with irritable bowel syndrome (IBS) are being randomized to a yogic breathing or control condition. Participants randomized to the yogic breathing group will be asked to complete a 2-minute yogic breathing video 5 to 7 days per week at home for 4 weeks and control group participants will be asked to maintain their current activities. Participants in this group will be given access to the yogic breathing video at the end of the 4-week control period. IBS symptoms and autonomic and vascular function will be assessed at baseline and at the end of week 4 in both groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
盲法说明
Members of the investigative team will be blinded to the participant's group assignment until all testing is completed.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Must have a formal diagnosis of IBS and not be enrolled in any other clinical trials.
排除标准
- •current, regular practice of yogic breathing at least 5 minutes per day and 2) chronic obstructive pulmonary disease
研究组 & 干预措施
Yogic breathing intervention
Participants assigned to this group will complete a 20-minute yogic breathing video at least 5 days per week for 4 weeks. All sessions except the initial yogic breathing session will be completed at home. Participants will complete the first session at Texas State under the supervision of the investigative team for familiarization.
干预措施: Yogic breathing intervention (Behavioral)
Control
Participants in the control group will be asked to maintain their current daily activities and will be given access to the yogic breathing video once all follow-up testing has been completed at the end of week 4.
结局指标
主要结局
Autonomic function
时间窗: Once at the end of week 4
Heart rate variability will be assessed.
Microvascular function
时间窗: Once at the end of week 4
Laser Doppler flowmetry and in response to local heating will be measured.
IBS Symptoms
时间窗: Once at the end of week 4
IBS-Symptom Severity Scale will be administered.
IBS Symptoms
时间窗: Once at baseline
IBS-Symptom Severity Scale will be administered.
Autonomic function
时间窗: Once at baseline
Heart rate variability will be assessed.
IBS Symptoms
时间窗: Once at the end of week 2
IBS-Symptom Severity Scale will be administered.
Autonomic function
时间窗: Once at the end of week 2
Heart rate variability will be assessed.
Microvascular function
时间窗: Once at baseline
Laser Doppler flowmetry at baseline and in response to local heating will be measured.
次要结局
未报告次要终点