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Clinical Trials/NCT01924403
NCT01924403CompletedNot Applicable

Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty Using SPY Intra-operative Angiography

Mayo Clinic1 site in 1 country45 target enrollmentStarted: August 1, 2013Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
45
Locations
1
Primary Endpoint
Perfusion of Wound Closure

Study Overview

Brief Summary

This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion. This can be achieve by using SPY intra-operative vascular angiography, which is commonly used in clinical practice to assess perfusion of wound closure at the clinic. By understanding the differences in perfusion afforded by different closure techniques, surgeons will then be able to select the technique that optimizes this parameter so as to avoid complications such as tissue necrosis, wound dehiscence, or infection.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •≥ 18 years old
  • •Primary diagnosis of osteoarthritis
  • •Surgical indication for index total knee arthroplasty

Exclusion Criteria

  • •Previous surgery about the knee
  • •Systemic corticosteroid use
  • •Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis

Arms & Interventions

Staple Closure

Experimental

Staple closure will be one technique employed to close the wound in primary total knee arthroplasty.

Intervention: Staple Closure (Procedure)

Running Subcuticular Closure

Experimental

Running subcuticular closure will be one technique employed to close the wound in primary total knee arthroplasty.

Intervention: Running Subcuticular Closure (Procedure)

Vertical Mattress Closure

Experimental

Vertical mattress closure will be one technique employed to close the wound in primary total knee arthroplasty.

Intervention: Vertical Mattress Closure (Procedure)

Outcomes

Primary Outcomes

Perfusion of Wound Closure

Time Frame: Surgical Point of Care

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Robert T. Trousdale

Professor of Orthopedic Surgery

Mayo Clinic

Study Sites (1)

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