Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty Using SPY Intra-operative Angiography
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Mayo Clinic
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Perfusion of Wound Closure
Study Overview
Brief Summary
This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion. This can be achieve by using SPY intra-operative vascular angiography, which is commonly used in clinical practice to assess perfusion of wound closure at the clinic. By understanding the differences in perfusion afforded by different closure techniques, surgeons will then be able to select the technique that optimizes this parameter so as to avoid complications such as tissue necrosis, wound dehiscence, or infection.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •≥ 18 years old
- •Primary diagnosis of osteoarthritis
- •Surgical indication for index total knee arthroplasty
Exclusion Criteria
- •Previous surgery about the knee
- •Systemic corticosteroid use
- •Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis
Arms & Interventions
Staple Closure
Staple closure will be one technique employed to close the wound in primary total knee arthroplasty.
Intervention: Staple Closure (Procedure)
Running Subcuticular Closure
Running subcuticular closure will be one technique employed to close the wound in primary total knee arthroplasty.
Intervention: Running Subcuticular Closure (Procedure)
Vertical Mattress Closure
Vertical mattress closure will be one technique employed to close the wound in primary total knee arthroplasty.
Intervention: Vertical Mattress Closure (Procedure)
Outcomes
Primary Outcomes
Perfusion of Wound Closure
Time Frame: Surgical Point of Care
Secondary Outcomes
No secondary outcomes reported
Investigators
Robert T. Trousdale
Professor of Orthopedic Surgery
Mayo Clinic
