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Clinical Trials/NCT02348671
NCT02348671
Completed
Not Applicable

Evaluation of Wound Dressings to Reduce the Harmful Effects of Shear- Force at the Skin

Maastricht University Medical Center0 sites10 target enrollmentMarch 2015
ConditionsPressure Ulcer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pressure Ulcer
Sponsor
Maastricht University Medical Center
Enrollment
10
Primary Endpoint
Cutaneous blood flow, erythema index, IL-1alpha/Total protein ratio
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The purpose of this study is to investigate if wound dressings are capable in reducing the effects of shear- force at the skin. With our own shear- force model we are able to apply 19 Newton shear- force combined with 9 newton pressure at the skin of the non- dominant forearm. After half an hour we measure IL-1alpha/ total protein- ratio, cutaneous blood flow (Laser doppler, Moor LDI) and the erythema index (DSMIIColormeter) which occurs as an effect of shear- force application at the skin.

Then, we apply 19 Newton shear- force combined with 9 Newton pressure at the dominant fore-arm but this time we put a wound dressing between the skin and shear- force model. After half an hour we measure the IL-1alpha/total protein-ratio, cutaneous blood flow and the erythema index.

This research consists of three research day, each day we are going to investigate a different wound dressing

Registry
clinicaltrials.gov
Start Date
March 2015
End Date
July 2015
Last Updated
10 years ago
Study Type
Observational
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • healhty volunteer
  • age 18- 30
  • BMI 20- 30

Exclusion Criteria

  • Trauma fore-arms
  • Diabetes mellitus type I or type II
  • The use of NSAID's in the last 7 days
  • Vascular diseases
  • Muscular dystrophy
  • Malignancy
  • Participant is unable to give informed consent

Outcomes

Primary Outcomes

Cutaneous blood flow, erythema index, IL-1alpha/Total protein ratio

Time Frame: Directly after intevention

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