Identification of Noninvasive Biomarkers for Neonates Undergoing Abdominal Surgery

Recruiting

• Conditions: Neonate; Biomarkers

• Registration Number: NCT05181423
• Lead Sponsor: West China Hospital

Brief Summary

To identify the potential serum and radiological biomarkers with regard to neonates undergoing abdominal surgery, and to further evaluate the prognostic value of these markers.

Detailed Description

First, the investigators will collect serum biomarkers in neonate patients receiving abdominal surgery. Then the investigators will identify the characteristics and change of biomarkers expressed in neonate patients before and after abdominal surgery. The investigators will further evaluate the prognostic value of these markers for neonate patients receiving abdominal surgery.

Study Timeline

• Study Start: 2021-01-01
• Study First Submitted: 2021-12-19
• Study First Submitted QC: 2021-12-19
• Status Verified: 2022-01
• Last Update Submitted: 2022-01-05
• Study First Posted: 2022-01-06
• Last Update Posted: 2022-01-20
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Age up to 18 years old
• With written informed consent

Exclusion Criteria

• Clinical data missing
• Without written informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Value of non-invasive biomarkers	At least 5-year follow up	These markers will be collected in association with the prognostication for neonates before and after surgery.

Trial Locations

Locations (1)

West China Hospital, Sichuan University; 🇨🇳 Chengdu, Sichuan, China