Full Thickness Mucoperiosteal Flap Versus Low Level Laser in Orthodontic Tooth Movement Acceleration

Not Applicable

Completed

• Conditions: Mesial Movement of Teeth
• Interventions: Device: low level laser therapy; Procedure: elevation of full thickness mucoperiosteal flap

• Registration Number: NCT04055935
• Lead Sponsor: Al-Azhar University

Brief Summary

This study aimed to evaluate the effect of using full thickness mucoperiosteal flap (FTMPF) elevation only versus low level laser therapy (LLLT) on acceleration of orthodontic tooth movement.

Detailed Description

This study was a split mouth design study included 32 side according to sample size calculation. Those sides were divided into 2 groups. Group 1divided into (group 1a: 8 sides with FTMPF, group 1b:8 sides control). Group 2(group 2 a: 8 sides with LLLT, group 2b: 8 sides control). Extraction of the first maxillary premolars followed by canine retraction in the extraction space with maximum anchorage were indicated. FTMPF was elevated from the mesial interdental papilla of maxillary canine to the mesial interdental papilla of second maxillary premolar. LLLT was applied at 3,7,14,28.56 days of retraction. During retraction study model for all patients were taken at 2ed, 6th, 14th,16th weeks and at the end of retraction (I1,I2,I3,I4,I5 or overall interval). 3D laser scanning and digital superimposition was done to measure the rate of canine retraction and anchorage loss.

Study Timeline

• Study Start: 2017-09-01
• Primary Completion: 2019-04-01
• Study Completion: 2019-06-01
• Study First Submitted: 2019-07-30
• Status Verified: 2019-08
• Study First Submitted QC: 2019-08-12
• Study First Posted: 2019-08-14
• Last Update Submitted: 2019-08-18
• Last Update Posted: 2019-08-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 32

Inclusion Criteria

• o Free of any syndromes affecting the head region or any craniofacial injuries.

  • No history of previous orthodontic treatment
  • All of the permanent dentition present excluding third molars.
  • Good oral hygiene before starting treatment.
  • Cases indicated for extraction of the maxillary first premolars and canine retraction into the extraction space with maximum anchorage.
  • Malocclusion cases that allow initial stage of leveling and alignment without extraction.

Exclusion Criteria

• o Patients with systemic diseases especially bleeding disorders and osteoporosis.

  • History of administration of corticosteroids, exogenous hormones and non-steroidal anti-inflammatory drugs (all drugs interfere with OTM).
  • Presence of previous history of oral surgeries in maxillary arch.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
low level laser therapy	low level laser therapy	LLLT was done using a diode soft laser (Epic X, BioLase, USA). It is a semiconductor diode soft laser. Active medium is In-Ga-As with 940nm wave length
full thickness mucoperiosteal flap	elevation of full thickness mucoperiosteal flap	A full thickness mucoperiosteal flap (FTMPF) was reflected on FTMPF side at the maxillary canine/premolar region by the same surgeon for all patients following the same procedures.

Primary Outcome Measures

Name	Time	Method
rate of orthodontic tooth movement acceleration determination by measuring the rate of maxillary canine retraction	the rate of retraction( distance from the first day of retraction to the end of retraction/ time)) it was with total time frame 24 weeks for starting of retraction	measure the rate of canine retraction on series of study models

Secondary Outcome Measures

Name	Time	Method
clinical mesial movement of first maxillary molar measured by millimeter on the 3D model	t0(start of canine retraction) to 24 months	amount of mesial movement of first maxillary molar after 24 month

Trial Locations

Locations (1)

Faculty of dentistry ,Al-Azhar Univerisity; 🇪🇬 Cairo, Naser City, Egypt