Effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism
Not Applicable
Completed
- Conditions
- Acanthosis NigricansObesity
- Interventions
- Dietary Supplement: melatonin
- Registration Number
- NCT02604095
- Lead Sponsor
- Shanghai 10th People's Hospital
- Brief Summary
Effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism.
- Detailed Description
The effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism in patient with obesity and acanthuses nigrican.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- Age:18-60 years old;
- BMI ≥ 28 kg/m2；
- With acanthosis nigricans。
Exclusion Criteria
- With liver, kidney, gastrointestinal or other major organic serious diseases, cancer, lactating women, pregnancy.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Melatonin melatonin Take one table at bedtime.
- Primary Outcome Measures
Name Time Method insulin resistance index 12 weeks HOMA-IR:serum fasting insulin(mmol/L) × serum fasting glucose(mmol/L)/22.5
- Secondary Outcome Measures
Name Time Method Neck circumference 12 weeks Neck circumference (cm)
Triglyceride 12 weeks Triglyceride (mmol/L)
Low Density Lipoprotein 12 weeks Low Density Lipoprotein (mmol/L)
Blood pressure 12 weeks Systolic blood pressure (mmHg) and diastolic blood pressure (mmHg)
Waist circumference 12 weeks Waist circumference (cm)
High Density Lipoprotein 12 weeks High Density Lipoprotein (mmol/L)
Body weight 12 weeks Body weight (kg)
Body fat 12 weeks Body fat (%)
Total Cholesterol 12 weeks Total Cholesterol (mmol/L)
Trial Locations
- Locations (1)
Shanghai Tenth People' Hospital
🇨🇳Shanghai, Shanghai, China