MedPath

Safety and Efficacy Determination of Skin Lightening Set Treatment Products for Combination to Oily Ski

Phase 1
Completed
Conditions
Healthy Thai female subjects
Registration Number
TCTR20190617002
Lead Sponsor
nilever Thai Services Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Female
Target Recruitment
33
Inclusion Criteria

1. Healthy female volunteers in an age range of 25-35 years old with combination to oily skin
2. Free of any visible disease on the test area
3. Having dull skin, pigmentary dark sots on the face
4. Having experience using any counter brand product
5. No history of allergy against any components of trial products or other whitening cosmetics
6. Be able to use only provide products (exception for the normal products in other categories of their routine use) during the test period
7. No history of takingany functional supplement which improve skin condition and no skin treatment within 1 month prior the study
8. Be able to follow the study protocol
9. Willing to give a consent of the volunteer

Exclusion Criteria

1. History of eczema or psoriasis within 6 months
2. History of herbes
3. Incident of facial warts, wounds or scars
4. Medical or cosmetic treatment with steroids, antibiotics, NSAIDs, anti-histamine, azelaic acid, kojic acid, hydroquinone, chemical peels, tretinoin or isotretinoin within 4 weeks before the study
5. History of major operation within 1 year
6. History of skin cancer within 1 year
7. Pregnancy or lactation
8. Heavy smoker or drinker

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Skin irritation test 0, 0.5, 1, 24h 24 hours patch test,Quantification of the lightening effect week 0, 1, 4, 8 chromameter,Quantification of skin moisture week 0, 1, 4, 8 Corneometer,Quantification of melanin index week 0, 1, 4, 8 Mexameter ,Quantification of the Erythema value week 0, 1, 4, 8 Mexameter ,Visual evaluation week 0, 1, 4, 8 Digital photography,Satisfaction of scrub product usage week 1, 4, 8 Questionnaire form,skin type week 8 visual
Secondary Outcome Measures
NameTimeMethod
/A N/A N/A
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