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Clinical Trials/NCT05917626
NCT05917626
Recruiting
Not Applicable

Effectiveness and Implementation of a Digital Intervention for Pediatric Chronic Pain Co-designed With Patients

University of Malaga6 sites in 1 country195 target enrollmentMay 5, 2023
ConditionsChronic Pain

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Pain
Sponsor
University of Malaga
Enrollment
195
Locations
6
Primary Endpoint
Change in Pain Interference
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

Children and adolescents with chronic pain often lack a proper diagnosis and treatment. Research has shown that, if left untreated, it usually doesn't resolve and continues through adulthood.

The goal of this multi-phase study is to co-develop (with patients), test, and implement a smartphone app called "Digital Solution for Pain in Adolescents" (Digital SPA) which can provide pain management resources to children with chronic pain and their parents, preventing future disability.

Participants will: participate in individual and group interviews, respond to questionnaires online and try a smartphone app.

Detailed Description

Phase 1) Focus groups with patients, parents and clinicians (n = 5-6 each) will inform about unmet pain care needs, and provide a starting point for co-designing the intervention. Phase 2) Content creation and usability testing will be based on the results of Phase 1 and the theory-driven development will follow the latest available evidence and the World Health Organization guidelines on the management of chronic pain in children. The intervention will use validated psychological techniques (particularly Cognitive Behavioral Therapy and Acceptance and Commitment Therapy) focused on improving functioning by teaching pain coping skills, such as: relaxation, goal setting, sleep management, behavioral activation, self-management of negative thoughts and emotions, and communication skills. Phase 3) Effectiveness and Implementation study. Participants (n = 195) will be adolescents 12-17 years old with chronic pain admitted into any of 6 large hospitals in Spain and one of their parents.

Registry
clinicaltrials.gov
Start Date
May 5, 2023
End Date
October 1, 2027
Last Updated
4 months ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Rocio de la Vega de Carranza, PhD

"Ramón y Cajal" Researcher; Principal Investigator

University of Malaga

Eligibility Criteria

Inclusion Criteria

  • Adolescents age 12-17 years
  • Has had non-oncologic chronic pain for at least 3 months (e.g., abdominal pain, headache or musculoskeletal pain)
  • Has Internet access
  • One parent is willing to participate (and both give consent for their child to participate)

Exclusion Criteria

  • Diagnosis of a comorbid serious health condition (e.g., cancer)
  • Parent or child does not speak or read Spanish
  • Active psychosis or suicidal ideation

Outcomes

Primary Outcomes

Change in Pain Interference

Time Frame: Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).

Spanish version of the Brief Pain Inventory (BPI) short version. Pain intensity scale scores range from from 0 to 10 , with higher scores indicating greater interference. Interference scores range from 0 to 10, with higher scores indicating greater interference.

Global impression of change after treatment

Time Frame: Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).

11-point scale (0 to 10) with higher scores indicating greater impression of change.

Change in the number of visits to the Emergency Room (ER) due to pain

Time Frame: Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).

The number of visits to the ER due to pain during the follow-up period (T3 to T4; 3 months) will be compared with the three months before starting treatment (T1).

Secondary Outcomes

  • Change in pain readiness to change(Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Change in the dose of pain medication taken(Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Change in the type of pain medication taken(Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Change in Emotional Distress(Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Change in Functional Disability(Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Change in Sleep(Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Change in Pain Self-efficacy(Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Psychological Flexibility and Inflexibility Processes(Pre-treatment (T1), Mid-treatment (T2; 4 weeks after T1), Post-treatment (T3; 8 weeks after T1) and 3-months follow-up (T4; 3 months after T3).)
  • Satisfaction with treatment(Post-treatment (T3; 8 weeks after T1).)
  • Adherence to treatment(From the moment the treatment app is downloaded (T1), to the completion of the treatment period (T3). Up to 10 weeks.)

Study Sites (6)

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