The local effect of two antidepressant drugs on pain reduction in teeth with severe tooth ache ( irreversible tooth pulp inflammation) during root canal therapy.

Not Applicable

• Conditions: Irreversible pulpitis.; Diseases of pulp and periapical tissues-Pulpitis-irreversible

• Registration Number: IRCT201110317963N1
• Lead Sponsor: Research Center of Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

patient ( male or female )with a molar tooth with a pulpal and periapical diagnosis of symptomatic irreversible pulpitis; healthy patient with a non-contributory medical history; patient must not use any medicaments; must not have any allergy to the drugs used in this experiment or other tricyclic antidepressant; must not use tricyclic antidepressant; after administration of local anesthetic must still experience pain during the preparation of the access cavity.

exclusion criteria: patient ( male or female ) with any systemic disease; patient using any medicament; patient with allergy to the drugs used in this experiment or other tricyclic antidepressant; use of tricyclic antidepressant; after administration of local anesthetic does experience pain during the preparation of the access cavity.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: 5 minute after application of the drug. Method of measurement: VAS scale.