The effects of oxytocin on trust and aggressio
Phase 2
Completed
- Conditions
- aggressionantisocial behavior10034726
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
males between the ages of 18 and 35 years, in good health, and able to understand the informed consent as assessed by the study physician.
Exclusion Criteria
No mental disorder, current or past history of drug or alcohol abuse or dependence, history of hypersensitivity to oxytocin, presence of or history of clinically significant allergic rhinitis, smoke more than 10 cigarettes per day. Subjects will be excluded when they cannot understand the Dutch language sufficiently to understand the purposes and implications of the experiment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Outcome measures will be:<br /><br>1) points scored on the PSAP (oxytocin vs placebo)<br /><br>2) points scored on the Trust Game (oxytocin vs placebo)<br /><br>3) salivary levels in testosterone and cortisol<br /><br>4) urinary and serum levels of oxytocin</p><br>
- Secondary Outcome Measures
Name Time Method <p>Outcome measures on the different questionnaires:<br /><br>1) Personality, as measured on the *Neuroticism-Extroversion-Openness<br /><br>Inventory- Five Factor Inventory* (NEO-FFI).<br /><br>2) traits of psychopathy, as measured on the *Triarchic - Psychopathy<br /><br>Measure* (TriPM).<br /><br>3) attachment styles, as measured on the *Relationship Questionnaire* (RQ) and<br /><br>the 'Experiences in Close Relationships' vragenlijst (ECR)<br /><br>4) trust, as measured on the *Trust Inventory* (TI)<br /><br>5) aggression as measuren on the agressie vragenlijst (AVL)<br /><br>6) Mood state, measured on 2 moments during the experiment, measured on the<br /><br>*Profile Of Mood States* (POMS). </p><br>