A study of small fiber neuropathy (SFN): immunohistochemical changes of peripheral nerve fibers on biposied skin and correlation with inflammatory cytokine expressio
Not Applicable
- Conditions
- small fiber neuropathy
- Registration Number
- JPRN-UMIN000006639
- Lead Sponsor
- Department of Dermatology Saitama Medical Center, Saitama Medical University
- Brief Summary
Participants are not sufficiently enrolled before the retirement date of this investigator, resulting in withdrawal of this investigation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 3
Inclusion Criteria
Not provided
Exclusion Criteria
Patients diagnosed as not having SFN or other type of disturbance of peripheral nerves with greater diameter, or patients with disagreement are to be excluded from the study. .
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Epidermal nerve fiber density Immunohistochemical reactivity alteration in dermal and epidermal nerve fibers Cytokine expression in biopsied skin in protein and mRNA levels
- Secondary Outcome Measures
Name Time Method Morphological change in dermal and epidermal nerve fibers Cytokine expression in the peripheral blood in protein and mRNA levels