The effect of genistein supplementation on metabolic parameters and oxidative stress in postmenopausal women with type 2 diabetes.

Phase 2

• Conditions: Non-insulin-dependent type 2 diabetes; type 2 diabetes.

• Registration Number: IRCT201611033664N18
• Lead Sponsor: Vice-chancellor for research, Tabriz Nutrition Research Center, Tabriz University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Willingness to participate in the study; Postmenopausal women with history of at least one year menopause ; menopause must not be a complication of surgery; Type-2 diabetes for at least 6 months; using blood glucose lowering drugs (metformin) .
Exclusion criteria: Unwillingness to participate in the study; Surgery leads to menopause; Early menopause (before 40 years); Use of androgen and estrogen and other steroids can affect the estrogen receptor; Insulin injections; Use of any nutritional supplements (omega-3) or anti-inflammatory and antioxidant supplements in the last 3 months or during the study; Liver and kidney failure, cardiovascular disease, breast cancer and thyroid disease; Smoking and alcohol; Patients taking NSAID, corticosteroids (prednisone, methylprednisolone, and hydrocortisone), antidiuretic thiazide (furosemide and hydrochlorothiazide) and anti psychotics second generation (olanzapine, clozapine and).
(All participants in the study shouldn't take these drugs at least three months before the study)

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified