Comparing nerve block and systemic pain relievers for pain relief following total knee replacement
Not Applicable
- Conditions
- Health Condition 1: M171- Unilateral primary osteoarthritisof knee
- Registration Number
- CTRI/2020/01/022825
- Lead Sponsor
- MOSC Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.ASA I-III
2.Body mass index 20 - 35kg/m2
3.Advanced osteoarthritis of the knee joint â??Kellgren and Laurence stage III and IV
4.Total knee replacements with cruciate retaining implants
5.Willingness to take part in the study
Exclusion Criteria
1.Known allergy to the study drugs
2.Contraindication to Neuraxial blockade and Adductor canal block
3.Patients with cognitive impairment
4.Preexisting neuropathy on operating limb
5.Uncontrolled cardiovascular / hepatic / renal disease
6.Osteoarthritis of the knee joint with significant bone loss requiring bone grafts or augments during total knee arthroplasty
7.Significant osteoarthritis on the opposite knee or other joints which can affect the mobility of the patient.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post operative analgesia determined with visual analogue scores for painTimepoint: 6,12,18,24 and 48 hours postoperatively
- Secondary Outcome Measures
Name Time Method evel of patient satisfaction and Length of hospital stayTimepoint: at the time of discharge;quadriceps muscle strength using Medical Research Council Scale and to assess the adverse eventsTimepoint: 24 and 48 hours postoperatively