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临床试验/NCT06527040
NCT06527040尚未招募不适用

Clinical Decision Support for Safety of Opioid Transitions

University of Colorado, Denver1 个研究点 分布在 1 个国家目标入组 200,000 人开始时间: 2026年12月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
200,000
试验地点
1
主要终点
Percentage of encounters with an opioid transitioning prescription

研究概览

简要总结

The objective of this study is to evaluate the impact of a clinical decision support (CDS) alert designed to notify providers when an opioid prescription will result in a patient transitioning into a new phase of opioid therapy. The 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain recommends that providers reassess patient pain, treatment goals, and the risks and benefits of opioid therapy before patients transition from acute to subacute treatment (1 month of opioid analgesics) and from subacute to chronic opioid treatment (3 months). This study will evaluate a CDS tool that identifies patients who will be transitioning between phases of opioid therapy as a result of a prescribed opioid medication and prompts providers to review patient needs and goals of care. A pre-post study design will be used to compare provider prescribing practices and patient outcomes before and after implementation of the CDS alert. During the pre-implementation period, providers will continue routine care and will have access to existing patient pain assessments and clinical information, but no transition alert will be displayed. During the post-implementation period, providers will receive a notification when an opioid prescription results in a transition to a new phase of therapy and will be encouraged to review patient needs, reassess pain and treatment goals, and document their clinical decision-making. Opioid transition orders, provider documentation, and patient outcomes will be evaluated using medical record data collected during routine clinical care and compared between the pre-implementation and post-implementation periods.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
12 Years 至 89 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Any primary care encounter where an opioid is prescribed that transitions the patient to a different stage of opioid therapy (acute to subacute after 1 month of opioids; subacute to chronic after 3 months of an opioid)

排除标准

  • •Patients <12 and >89
  • •Patients with active cancer diagnosis in last 1 year
  • •Patients with hospice care/palliative care order
  • •Patients with sickle cell disease diagnosis

研究组 & 干预措施

pre-implementation period

Encounters with a high risk opioid prescription prior to intervention implementation. Providers will not see any alert. Usual care.

Clinical Decision Support (CDS): Opioid transition alert

Encounters where the opioid transition clinical decision support (CDS) alert fired. CDS logic is programmed to fire the alert when a provider places an order for an opioid that will transition the patient from acute to subacute opioid therapy (at 30 days) or from subacute to chronic opioid therapy (at 90 days).

干预措施: Opioid Transitions Clinical Decision Support (CDS) (Other)

结局指标

主要结局

Percentage of encounters with an opioid transitioning prescription

时间窗: 18 months

The number of primary care encounters where an opioid prescription transitions a patient to a different phase of care (by phase) divided by the total number of opioid prescriptions

次要结局

  • Opioid prescription abandonment(18 months)
  • Number of patients with long term opioid use(Six months after an encounter where the opioid use disorder is identified)
  • Clinical decision support (CDS) acceptance rate(18 months)
  • Subsequent opioid overdose/poisoning rates(Six months after an encounter where the opioid use disorder is identified)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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