跳至主要内容
临床试验/NCT01148485
NCT01148485已完成不适用

Community-acquired Methicillin-Resistant Staphylococcus Aureus Carriage Among Athletes: a Study in Limousin. : CA-MRSA

University Hospital, Limoges0 个研究点目标入组 300 人开始时间: 2011年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
300
主要终点
Presence of Methicillin-Resistant Staphylococcus aureus in the samples.

研究概览

简要总结

There are only very few data about the prevalence of CA-MRSA in France and no in athletes. In USA, the clone USA300 is widely disseminated and in Europe the clone ST80 predominates. The aim of the study was to study the carriage of S. aureus in athletes in a French county (Limousin) and to evaluate the proportion of CA-MRSA. The athletes will be met during their training, each one will fill-in a clinical information questionnaire. Nasal, throat, inguinal and skin lesions swab samples will be performed. The antibiotic susceptibility profile of the Staphyloccocus aureus strains isolated will be performed as well as the detection of the PVL gene. Strains will also be typed by different molecular methods (PGFE (Pulsed Gel Field Electrophoresis), SCCmec type (Staphylococcal Chromosome Cassette mec), and MLST (MultiLocus Sequence Typing)). The CIC (Clinical Investigation Center) of the Limoges University Hospital will be in charge of the inclusions of the athletes. The sample analysis will be centralized and performed at the Laboratory of Bacteriology of the Limoges University Hospital. A Clinical Research Officer of the Limoges University Hospital will be in charge of the survey of the study and will organize monthly meetings with all the participants of the study.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients (over 18),
  • belonging to a sport club of Limousin, practicing rugby, wrestling, basket-ball, volley-ball, hand-ball, fence, martial art, football, weight lifting, and base-ball.
  • Patient having signed in a free way and lit his consent to participate in this study

排除标准

  • clinical information questionnaire not possible to fill,
  • swab sample not possible to realize.

结局指标

主要结局

Presence of Methicillin-Resistant Staphylococcus aureus in the samples.

时间窗: 1 year

An athlete is defined as a carrier if at least one strain of Staphylococcus aureus is isolated from one of these samples. A MRSA carrier is defined if the resistance to methicillin has been found for the S. aureus strain isolated in the patient.

次要结局

  • Comparison of the MRSA prevalence in athletes according to the sport(1 year)

研究者

发起方
University Hospital, Limoges
申办方类型
Other
责任方
Sponsor

相似试验