Assessment of body-composition in five year-old children: Validity and reliability of Bioelectrical Impedance Analysis (BIA) compared to three compartment model based on air-displacement plethysmography (BOD POD) and deuteriumwater (D2O).

Recruiting

Conditions: (predictie van) overgewicht/obesitas, diabetes en hart en vaatziekten
Body composition
overweight

Registration Number: NL-OMON33201

Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 50

Inclusion Criteria

Age 5 jaar
Explanation of the studie, informed consent and the study itself will be done by research physicians who have extensive experience in (clinical) research in children.

Exclusion Criteria

Other age groups
No informed consent
Inability of cooperation or lack of cooperation

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome variables are body composition as determined with BIA and<br /><br>BOD POD respectively. These will be compared with body composition as<br /><br>determined by deuterium dilution. Comparison will be performed by using:<br /><br>- graphical comparison (XY plots of BIA versus D2O and BOP POD versus D2O) and<br /><br>- using regression analysis with BIA and BOD POD as dependant variables,<br /><br>respectively and D2O as independent variable.<br /><br>- root mean square prediction of error (RMSE)<br /><br>- Concordance correlation coefficient (CCC).<br /><br>- Bland Altman plot (bias and limits of agreement).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>As secondary outcome measures we will compare BIA versus SFT, botpot versus<br /><br>SFT, BIA versus WHtR, BOD POD versus WHtR and BMI versus WHtR, using:<br /><br>Pearson product moment correlations.<br /><br>Bland Altman plot (bias and limits of agreement).<br /><br>Because of gender specific normal values, BMI will be assessed for boys and<br /><br>girls separately. Age is standardized (all children are age 5). Waist to height<br /><br>ratio is standardized, independent of age and gender.</p><br>