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临床试验/NCT02164799
NCT02164799已完成不适用

Establishing a Tool to Increase the Accuracy of Emergency Physicians Diagnosing Etiologies of Shock

Beth Israel Deaconess Medical Center0 个研究点目标入组 2,500 人开始时间: 2012年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
2,500
主要终点
Etiology of Shock

研究概览

简要总结

The Shock Tool study is designed to improve the clinical evaluation for differentiating shock in the emergency department. The goal of this study is to evaluate and improve the accuracy of physicians differentiating causes of shock.

详细描述

Specific Aim #1: To study the epidemiology of shock in the emergency department Hypothesis 1: We will better understand shock states if we determine shock etiology among patients presenting to the emergency department in a carefully conducted observational prospective study.

Specific Aim #2: To determine the accuracy of physician diagnosis for the underlying etiology of shock.

Hypothesis 2: Physician assessment of the underlying cause of shock is challenging and often inaccurate in the early stages of care in the emergency department.

Specific Aim #3: To optimize the evidence-based approach to assist in the diagnosis of shock etiology from elements readily available when a patient demonstrates shock physiology in the Emergency Department.

Hypothesis 3: An evidenced-based, standardized approach to clinical decision making integrating elements of the history, physical exam, and early testing will improve a physician's ability to accurately differentiate etiologies of shock.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18 years or great
  • For pre-shock cohort: HR > 130, RR>24, Shock index > 1, lactate > 4.0mmol/L, SBP < 90mm/hg)
  • For shock cohort: persistent blood pressure <90mm/hg after resuscitation

排除标准

  • isolated atrial fibrillation with discharge after rate control achieved
  • discharged from the emergency department
  • intoxication or withdrawal

结局指标

主要结局

Etiology of Shock

时间窗: Retrospectively, 1 month after enrollment

Each patient determined to have shock in the emergency department is given a single diagnosis by a reviewing physician after the hospital course is completed.

次要结局

  • In hospital mortality(This measure will be assessed at the time of physician review after discharge from hospital, on average 2 months after initial ED visit.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Daniel Henning

Instructor of Medicine

Beth Israel Deaconess Medical Center

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