Osseointegration of Maxillary Dental Implants in Diabetes Mellitus Patients: A Human Histomorphometric Study

Phase 1

Recruiting

• Conditions: Type 2 diabetes mellitusOsseointegration of dental implant and bone implant contact calculation; bone to implant contact; dental implants; healing around dental implants; insulin resistance; type 2 diabetes mellitus

• Registration Number: TCTR20190103004
• Lead Sponsor: Faculty of Dentistry

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-03
• Study Completion: 2019-06-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

type 2 diabetes for test group
Physically healthy (ASA I or II classification)
Psychological and emotional stable
No history of bone fracture during the last 12 months
Tooth loss at upper premolar or molar area (at least 6 months removal) & seek dental implant placement
Sufficient keratinized gingival at least 4 mm
Alveolar bone width of at least 6 mm and height of 12 mm (by CBCT)
No bone augmentation procedure needed before and during implant placement
Stable dental occlusion

Exclusion Criteria

Pregnant or lactating females
Use of anti-inflammatory and immunosuppressive drugs
HIV
Current smoking or ex-smoker
Patients with major complications of Diabetes (Cardiovascular and peripheral vascular disease, neuropathy and nephropathy)
History of chemotherapy or radiotherapy around head and neck area
Third molar and anterior edentulous area

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bone implant contact two months after micro implant placement bone histomorphometry

Secondary Outcome Measures

Name	Time	Method
dental implant stability after conventional implant placement Implant stability quotient (ISQ) measurement