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Improving Medication Adherence Through a Health Literacy-based Intervention for Coronary Heart Disease Patients

Not Applicable
Conditions
Coronary Disease
Interventions
Behavioral: Health literacy-based intervention
Registration Number
NCT04004546
Lead Sponsor
Chinese University of Hong Kong
Brief Summary

This is a multi-center pilot study to examine the effectiveness of a health literacy-based intervention to improve medication adherence and self-efficacy of medication use among individuals with coronary heart disease (CHD). The specific aims are to: i) develop a health literacy-based intervention to improve medication adherence for CHD individuals with low health literacy and ii) evaluate the effects of a health literacy-based intervention on improving medication adherence and self-efficacy in CHD individuals.

Detailed Description

The project will be conducted in 2 phases. Phase 1 is to develop the health literacy-based intervention that consists of a video and an education booklet. Phase 2 is to conduct a pilot study to evaluate the effectiveness of the intervention. A total of 60 participants with low health literacy and diagnosed with CHD will be recruited in two settings. Data will be collected at baseline and 4-weeks after enrollment. The following data will be collected:

At baseline: Socio-demographic information (e.g. age, gender, education level, income, past medical history, social support), health literacy (eligibility screening at time of recruitment), CHD knowledge, medication adherence, and medication self-efficacy.

4-weeks after enrollment: medication self-efficacy and medication adherence.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Aged ≥18 years and diagnosed with CHD.
  • Currently receiving pharmacological therapy such as statins, anti-platelet and/or blood thinner, beta-blockers, calcium channel blockers, nitroglycerin, and angiotensin- converting enzyme inhibitors (ACE).
  • Low health literacy score of 9 or less as measured using the short-form Mandarin Health Literacy Scale (s-MHLS).
Exclusion Criteria
  • History of significant cognitive impairment, psychiatric disorders, and aphasia.
  • Without access to a telephone or unable to give telephone contact.
  • Currently enrolled in another program or clinical trial.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Intervention groupHealth literacy-based interventionAt baseline: video and education booklet. 2-weeks after enrollment: telephone call by nurse.
Primary Outcome Measures
NameTimeMethod
Change from baseline medication adherence at 4-weeks follow-upBaseline and 4-weeks follow-up

Measured using the Chinese version of the Hill-Bone Medication Adherence Scale (HB-MAS). The HB-MAS is a self-reported measure of the extent of medication adherence. The HB-MAS consists of 9 questions with each item rated on a 4-point scale (1 = none of the time; 2 = some of the time; 3 = most of the time; and 4 = all of the time). The total score ranges from 9 (minimum) to 36 (maximum), where lower scores indicate higher levels of medication adherence.

Secondary Outcome Measures
NameTimeMethod
Change from baseline medication self-efficacy at 4-weeks follow-upBaseline and 4-weeks follow-up

Measured using the Chinese version of the Self-Efficacy for Appropriate Medication Use (C-SEAMS). The C-SEAMS is a self-reported measure of the extent of confidence in taking medications. The C-SEAMS consists of 13 questions with each item rated on a 3-point scale (1 = not confident; 2 = somewhat confident; 3 = very confident). The total score ranges from 13 (minimum) to 39 (maximum), where higher scores indicate higher levels of self-efficacy for medication use.

Trial Locations

Locations (2)

School of Nursing, National Taiwan University

🇨🇳

Taipei, Taiwan

The Nethersole School of Nursing, The Chinese University of Hong Kong

🇭🇰

Sha Tin, New Territories, Hong Kong

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