A comparative study to assess the efficacy and safety of intrathecal bupivacaine alone, intrathecal bupivacaine plus dexmedetomidine and intra thecal bupivacaine plus magnesium sulfate for the prevention of post spinal anaesthesia shivering in transurethral resection of prostate(TURP)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- To compare the efficacy of intrathecal bupivacaine alone, bupivacaine plus dexmedetomidine and bupivacaine plus magnesium sulfate group in terms of incidence and intensity of shivering
研究概览
简要总结
This study " A comparative study to assess the efficacy and safety of intrathecal bupivacaine alone, intrathecal bupivacaine plus dexmedetomidine and intrathecal bupivacaine plus magnesium sulfate for the prevention of post spinal anaesthesia shivering in transurethral resection of prostate (TURP)" will be done at Dr SN Medical college and associated group of hospitals Jodhpur (Rajasthan), after obtaining informed consent from the patients, under the guidance of my guide and the study is approved by institutional ethical committee -Dr Sampurnanand Medical College Jodhpur. There will be no financial burdon on the patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Male
入选标准
- •Male patients of ASA grade I and II of age 18-60 years posted for transurethral resection of prostate suitable for administration of regional anaesthesia.
排除标准
- •Patients refusal, BMI>28.0, spinal abnormality, patients with CKD, any contraindication to spinal anaesthesia like sepsis, abnormal coagulation profile, emergency surgery, infection at site of injection, allergy to local anaesthetics.
结局指标
主要结局
To compare the efficacy of intrathecal bupivacaine alone, bupivacaine plus dexmedetomidine and bupivacaine plus magnesium sulfate group in terms of incidence and intensity of shivering
时间窗: 3 Months
次要结局
- To compare the safety of intrathecal bupivacaine alone, bupivacaine plus dexmedetomidine and bupivacaine plus magnesium sulfate group in terms of hypothermia sedation score and complication including hypotension, bradycardia, nausea, vomiting and total dose of pethidine required to control shivering(3 months)